منابع مشابه
Genetic analysis of the larval optic nerve projection in Drosophila.
The Drosophila larval optic nerve, called Bolwig's nerve (BN), projects into the central brain along a simple invariant path. The growth of the BN proceeds in three phases, during which the nerve changes direction at two intermediate targets, P1 and P2. Here we show that the projection of the BN is amenable to genetic dissection. In a mutagenesis screen, we have isolated mutations in 13 genes t...
متن کاملGABA and development of the Xenopus optic projection.
In the developing visual system of Xenopus laevis retinal ganglion cell (RGC) axons extend through the brain towards their major target in the midbrain, the optic tectum. Enroute, the axons are guided along their pathway by cues in the environment. In vitro, neurotransmitters have been shown to act chemotropically to influence the trajectory of extending axons and regulate the outgrowth of deve...
متن کاملAbsence of transient receptor potential vanilloid-1 accelerates stress-induced axonopathy in the optic projection.
How neurons respond to stress in degenerative disease is of fundamental importance for identifying mechanisms of progression and new therapeutic targets. Members of the transient receptor potential (TRP) family of cation-selective ion channels are candidates for mediating stress signals, since different subunits transduce a variety of stimuli relevant in both normal and pathogenic physiology. W...
متن کاملFiber Optic Projection-Imaging System for Shape Measurement in Confined Space
A fiber-based projection-imaging system is proposed for shape measurement in confined space. Owing to the flexibility of imaging fibers, the system can be used in special scenarios that are difficult for conventional experimental setups. Three experiments: open space, closed space, and underwater are designed to demonstrate the strength and weakness of the system. It is shown that when proper a...
متن کاملThe formation of the optic fibre projection after partial tectal removal in Xenopus.
The formation of retinotectal connexions in Xenopus has been investigated by mapping the visual field projections of animals after various partial tectal removals. Following removal of a sufficiently extensive piece of the left rostral, caudal, medial or lateral tectum with, in addition, section of the contralateral optic nerve, a consistent defect in the nasal, temporal, superior or inferior v...
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ژورنال
عنوان ژورنال: Science
سال: 1915
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.41.1054.395